Mitral annular calcification in the elderly – Quantitative assessment

PurposeTo determine the reliability of subjective and objective quantification mitral annular calcification (MAC) in elderly patients with severe aortic stenosis, to define quantitative sex- age-related reference values MAC, correlate MAC valve disease.MethodsIn this retrospective, IRB-approved study, we included 559 (268 females, median age 81 years, inter-quartile range 77–85 years) stenosis undergoing CT. Four independent readers performed categorization as follows: no, mild, moderate, MAC. Two evaluation using Agatston score method (AgatstonMAC). Mitral disease was determined by echocardiography.ResultsSubjective showed high inter-reader agreement for no (k ​= ​0.88) ​0.75), whereas moderate ​0.59) mild ​0.45) moderate. Intra-reader substantial ​0.69 0.62). Inter- intra-reader AgatstonMAC were excellent (ICC ​0.998 0.999, respectively), minor inconsistencies involving left ventricular outflow tract/aortic valve. There significantly more women than men (n ​227, 85% versus n ​209, 72%; p ​< ​0.001), a higher (median 597, 81–2055 244; 0–1565; particularly ≥85 years age. an area-under-the-curve 0.84 diagnose there association regurgitation (p ​> ​0.05).ConclusionsOur study shows that scoring is reliable assessment. Women show scores men, population. accuracy stenosis.